Gavin P Robertson Selected Research

dehydroabietylamine

4/2017	Identifying the structure-activity relationship of leelamine necessary for inhibiting intracellular cholesterol transport.
1/2017	Targeting cholesterol transport in circulating melanoma cells to inhibit metastasis.
10/2014	Nanolipolee-007, a novel nanoparticle-based drug containing leelamine for the treatment of melanoma.
7/2014	Targeting multiple key signaling pathways in melanoma using leelamine.
7/2014	Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport.

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Gavin P Robertson Research Topics

Disease

61	Neoplasms (Cancer) 03/2022 - 07/2004
56	Melanoma (Melanoma, Malignant) 03/2022 - 06/2003
7	Neoplasm Metastasis (Metastasis) 01/2021 - 08/2006
5	Carcinogenesis 01/2019 - 06/2003
4	Skin Neoplasms (Skin Cancer) 10/2017 - 04/2007
2	Inflammation (Inflammations) 01/2022 - 06/2010
2	Leukemia 01/2020 - 10/2015
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020 - 10/2015
2	Niemann-Pick Diseases (Niemann Pick Disease) 08/2017 - 01/2017
2	Nevus (Nevi) 08/2010 - 05/2008
2	Breast Neoplasms (Breast Cancer) 06/2008 - 01/2008
2	Tuberous Sclerosis (Bourneville's Disease) 09/2006 - 07/2004
1	Disease Susceptibility (Diathesis) 01/2021
1	Hematologic Neoplasms (Hematological Malignancy) 01/2020
1	Malaria 08/2015

Drug/Important Bio-Agent (IBA)

34	Proteins (Proteins, Gene)FDA Link 03/2022 - 06/2003
13	Phosphotransferases (Kinase)IBA 03/2022 - 03/2005
13	Pharmaceutical PreparationsIBA 01/2022 - 05/2008
13	Mitogen-Activated Protein KinasesIBA 07/2014 - 09/2003
12	Small Interfering RNA (siRNA)IBA 09/2014 - 10/2004
8	CholesterolIBA 03/2022 - 07/2014
7	Protein Isoforms (Isoforms)IBA 01/2022 - 10/2004
6	EnzymesIBA 02/2020 - 09/2008
6	SeleniumIBA 07/2012 - 05/2008
5	dehydroabietylamineIBA 04/2017 - 07/2014
4	Drug CombinationsIBA 01/2018 - 07/2012
4	Biomarkers (Surrogate Marker)IBA 01/2017 - 01/2013
4	CeramidesIBA 03/2012 - 05/2005
3	LigandsIBA 01/2022 - 01/2008
3	CalreticulinIBA 01/2022 - 03/2011
3	AldehydesIBA 02/2020 - 10/2019
3	Oxidoreductases (Dehydrogenase)IBA 02/2020 - 10/2019
3	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2020 - 06/2003
3	Aldehyde DehydrogenaseIBA 10/2019 - 10/2015
3	Celecoxib (Celebrex)FDA Link 01/2017 - 01/2013
3	DNA (Deoxyribonucleic Acid)IBA 10/2015 - 08/2009
3	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 07/2012 - 08/2009
3	SulfurIBA 02/2011 - 03/2009
3	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 06/2008 - 08/2006
2	Indicators and Reagents (Reagents)IBA 01/2022 - 01/2019
2	Proline (L-Proline)FDA Link 01/2020 - 10/2015
2	Ornithine-Oxo-Acid Transaminase (Ornithine Aminotransferase)IBA 01/2020 - 10/2015
2	Casein Kinase II (Casein Kinase 2)IBA 01/2020 - 10/2015
2	capivasertibIBA 01/2018 - 01/2017
2	adavosertibIBA 01/2018 - 01/2017
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2017 - 01/2008
2	CyclinsIBA 01/2017 - 01/2017
2	plumbaginIBA 01/2017 - 01/2017
2	Phosphatidylinositols (Phosphatidylinositol)IBA 07/2014 - 12/2009
2	Mutant Proteins (Protein, Mutant)IBA 04/2013 - 03/2005
2	Sunscreening Agents (Sunscreens)IBA 01/2012 - 02/2011
2	IsothiocyanatesIBA 02/2011 - 03/2009
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2011 - 07/2010
2	IntegrinsIBA 01/2011 - 07/2010
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2010 - 03/2005
2	TensinsIBA 12/2009 - 06/2003
2	MitogensIBA 08/2009 - 01/2008
2	Liposomes (Liposome)IBA 08/2009 - 05/2005
2	Sorafenib (BAY 43-9006)FDA Link 06/2008 - 08/2006
2	MAP Kinase Kinase Kinases (MAP Kinase Kinase Kinase)IBA 01/2008 - 08/2006
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 09/2006 - 08/2006
2	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 10/2004 - 06/2003
2	Biological ProductsIBA 09/2003 - 06/2003
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Natural Killer Cell ReceptorsIBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	Myosin Light Chains (Myosin Essential Light Chain)IBA 01/2021
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2021
1	DNA Transposable Elements (Element, IS)IBA 01/2021
1	Sphingosine-1-Phosphate ReceptorsIBA 01/2021
1	4- ((3Z)- 3- ((5- (4- nitrophenyl)furan- 2- yl)methylidene)- 2- oxo- 5- phenylpyrrol- 1- yl)benzoic acidIBA 01/2020
1	Eukaryotic Initiation Factor-4G (Eukaryotic Initiation Factor 4G)IBA 01/2020
1	salubrinalIBA 01/2020
1	silmitasertibIBA 01/2020
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2020
1	Eukaryotic Initiation Factor-4F (EIF4F)IBA 01/2020
1	Eukaryotic Initiation Factor-4EIBA 01/2020
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2019
1	NucleotidesIBA 01/2019
1	PLIalphaIBA 01/2018
1	KetonesIBA 01/2018
1	piperidineIBA 01/2018
1	AcidsIBA 08/2017
1	Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA 08/2017
1	abietic acidIBA 04/2017
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2016
1	Therapeutic UsesIBA 10/2015
1	Ribosomal Proteins (Ribosomal Protein)IBA 09/2015
1	Amino Acids FDA Link 09/2015
1	RNA Polymerase I (Polymerase I, RNA)IBA 09/2015
1	AbietanesIBA 08/2015
1	Antimalarials (Antimalarial Agents)IBA 08/2015
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 10/2014
1	LipofuscinIBA 07/2014

Therapy/Procedure

20	Therapeutics 01/2022 - 06/2005
3	Drug Therapy (Chemotherapy) 01/2020 - 08/2009
3	Chemoprevention 10/2017 - 02/2011
2	Immunotherapy 01/2022 - 01/2019
1	Traction 04/2020
1	Radiotherapy 10/2019